Product info: Antibiotics - Doxycycline
Doxycycline: Doxycycline (VIBRAMYCIN) is a tetracycline antibiotic. It works by preventing the growth and spread of bacteria. Antibiotics will not work for colds, flu, or other viral infections. It fights bacteria in the body, including pneumonia and other respiratory tract infections. Doxycycline is used to treat many different bacterial infections, such as urinary tract infections, acne, gonorrhea, chlamydia, periodontitis (gum disease), and anthrax (after inhalational exposure) and others. Doxycycline may also be used for other purposes not listed in this medication guide.
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Doxycycline
Generic Name: Doxycycline anhydrous
Dosage Form: tablets
Rx only
To reduce the development of drug-resistant bacteria and maintain the effectiveness of Doxycycline tablets and other antibacterial drugs, Doxycycline tablets should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.
Doxycycline Description
Doxycycline is a broad-spectrum antibiotic synthetically derived from oxytetracycline. Doxycycline 150 mg, 100 mg, 75 mg, or 50 mg tablets contain Doxycycline monohydrate equivalent to 150 mg, 100 mg, 75 mg, or 50 mg of Doxycycline for oral administration. Inactive ingredients include anhydrous lactose, microcrystalline cellulose, corn starch, colloidal silicon dioxide, magnesium stearate, polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc, D&C yellow #10 aluminum lake, and FD&C yellow #6 aluminum lake. The chemical designation of the light-yellow crystalline powder is 4 - (Dimethylamino) - 1,4,4a,5,5a,6,11,12a - octahydro - 3,5,10,12,12a - pentahydroxy - 6 - methyl - 1,11 - dioxo - 2 - naphthacenecarboxamide monohydrate.
Structural formula:
Doxycycline has a high degree of lipid solubility and a low affinity for calcium binding. It is highly stable in normal human serum. Doxycycline will not degrade into an epianhydro form.
Doxycycline - Clinical Pharmacology
Tetracyclines are readily absorbed and are bound to plasma proteins in varying degrees. They are concentrated by the liver in the bile and excreted in the urine and feces at high concentrations in a biologically active form. Doxycycline is virtually completely absorbed after oral administration.
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